Inhibition of platelet aggregation by clopidogrel is totally as a result of an active metabolite. Clopidogrel is metabolized to this active metabolite in part by CYP2C19. .modafinil will raise the degree or result of rabeprazole by affecting hepatic enzyme CYP2C19 metabolism. Small/Significance Unfamiliar. Web effect on pantoprazole steps mysteriou